Group Photo

Welcome to the Laboratory of Igor Efimov

Cardiovascular disease is the leading cause of death in the industrialized world. Cardiovascular disease claims nearly a million lives of Americans annually. According to the World Health Organization, the gap between the cardiovascular cause of death and the others will widen in the 21 century. Sudden cardiac death occurs due to the development of fatal disturbances of cardiac rhythm known as arrhythmias, which often start as a tornado-like rotors of electrical activity rushing through the heart and spawning into numerous wavelets causing cardiac arrest. One of these cardiac "tornados" recorded in our laboratory is shown in the animation. The research in the laboratory is focused on advancing our understanding of the fundamental mechanisms of arrhythmogenesis, and on developing lifesaving antiarrhythmic therapies, including pharmacological agents and implantable devices.

The goals of our research laboratory:

  • To provide the best possible research environment for education of future biomedical engineers which will join academic and industrial research laboratories, heart clinics or start their own bio-tech businesses upon graduation from Washington University.
  • To conduct research investigation in the field of cardiac bioelectricity for the advancement of our understanding of heart disease and the development of better lifesaving therapies.
  • To serve the research community on panels, organizations, societies and boards for the advancement of national and international biomedical research and technology.
  • To translate scientific discoveries to the clinic and industry.

Rhythm:  MATLAB software for analyzing optical mapping data

3D Printing Physiology Laboratory Equipment:  Open-source repository of digital, experimental physiology equipment for 3D printing